In this expert lecture, Dr. Lai Hsin Chih explains the science behind extracellular vesicles (EVs) and exosomes, with a focus on probiotic-derived EVs as a safer and more scalable alternative to human and plant exosomes.
This session explores:
• What are EVs and exosomes?
• Key molecular components (miRNAs, lipids, proteins, metabolites)
• Differences between probiotic EVs and human/plant exosomes
• Regulatory considerations in cosmetic applications
• GMP production and purification workflow
A special focus is placed on Parabacteroides goldsteinii RV-01 extracellular vesicles (PG EVs), also referred to as “Golden Exosomes,” including:
• TEM imaging and size distribution analysis
• Multi-omics functional validation
• Reduction of TLR4-mediated inflammation
• UV stress protection
• Support of mitochondrial and metabolic pathways
This presentation highlights how next-generation probiotics and microbiome science are redefining innovation in skin care, immune modulation, and cellular longevity.
Extracellular Vesicles, EVs, Exosomes, Probiotic EVs, Bacterial Exosomes, Parabacteroides goldsteinii, Golden Exosomes, Microbiome Skincare, TLR4 Regulation, Inflammation Control, Mitochondrial Function, Next-Generation Probiotics